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Pathways Recommended:	Vitamin D Related/Nuclear Receptor

Results for "

Nuclear factor-kappaB

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Calcineurin (1)
By Research Areas:	Infection (1) Inflammation/Immunology (1) Neurological Disease (1)

1

Inhibitors & Agonists

1

Natural
Products

2

Recombinant Proteins

3

Antibodies

Targets Recommended: NF-κB Nuclear Factor of activated T Cells (NFAT) Nuclear Hormone Receptor 4A/NR4A

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

6,4'-Dihydroxy-7-methoxyflavanone	Calcineurin	Infection Neurological Disease Inflammation/Immunology
6,4'-Dihydroxy-7-methoxyflavanone, a flavonoid, is a nature product that could be isolated from Heartwood Dalbergia odorifera. 6,4'-Dihydroxy-7-methoxyflavanone inhibits receptor activators of nuclear factor kappa-B ligand (RANKL) induced osteoclastogenesis. 6,4'-Dihydroxy-7-methoxyflavanone has antioxidant, anti-inflammatory and neuroprotective effects. 6,4'-Dihydroxy-7-methoxyflavanone can be used in research of osteoporosis .

Species:	Human (2)
Tag:	GST (2)
Source:	Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

	IKKε Protein, Human (Sf9, GST) IKKε; Inhibitor of Nuclear factor kappa-B kinase subunit epsilon; I-kappa-B kinase epsilon; IKK-E; IKK-epsilon; IkBKE; Inducible I kappa-B kinase; IKK-i	Human	Sf9 insect cells
	IKKε protein is a serine/threonine kinase that coordinates the inflammatory response to viral infection by activating type I IFN, NF-kappa-B, and STAT signaling pathways. Upon activation of the viral RNA sensor, IKKε binds to DDX3X and phosphorylates IRF3, IRF7, and DDX3X, resulting in IRF3 nuclear translocation. IKKε Protein, Human (Sf9, GST) is the recombinant human-derived IKKε protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of IKKε Protein, Human (Sf9, GST) is 715 a.a., .

	IKKβ Protein, Human (Sf9, GST) IKBKβ; Inhibitor of Nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB; Serine/threonine protein kinase IKBKB	Human	Sf9 insect cells
	IKKβ protein is a serine kinase that is critical in the NF-kappa-B signaling pathway and can respond to various stimuli such as cytokines or cellular stress. As part of the classical IKK complex, IKKβ activates NF-kappa-B through phosphorylation inhibitors, leading to its degradation and release of NF-kappa-B for gene transcription. IKKβ Protein, Human (Sf9, GST) is the recombinant human-derived IKKβ protein, expressed by Sf9 insect cells , with N-GST labeled tag.

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